Primary HIV Infection, Phylogenetics, and Antiretroviral Prevention
نویسندگان
چکیده
منابع مشابه
Prevention of postnatal HIV infection: infant feeding and antiretroviral interventions.
PURPOSE OF REVIEW Mother-to-child transmission of HIV causes most paediatric HIV infections. Short-course peripartum antiretroviral therapy, available in resource-constrained settings, can reduce risk for transmission around the time of delivery. Acceptable, efficient and safe interventions aimed at reducing risk for postnatal HIV transmission through breast milk remain elusive, however. RECE...
متن کاملPrevention of HIV-1 infection with early antiretroviral therapy.
BACKGROUND Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. METHODS In nine countries, we enrolled 1763 couples in which one partner was HIV-1-positive and the other was HIV-1-negative; 54% of the subjects were from Africa, and 50% of infected partners were men. HIV-1-infected subjects ...
متن کاملPrevention of HIV-1 infection with antiretroviral therapy.
To the Editor: To recommend antiretroviral therapy (ART) as a policy to prevent transmission of the human immunodeficiency virus type 1 (HIV-1), it is critical to understand the risk of transmission through sex without condom use when the plasma viral load in patients receiving ART is fully suppressed. In addition to data reported by Cohen et al. (Aug. 11 issue),1 a 2009 meta-analysis2 showed n...
متن کاملShort-course antiretroviral therapy in primary HIV infection.
BACKGROUND Short-course antiretroviral therapy (ART) in primary human immunodeficiency virus (HIV) infection may delay disease progression but has not been adequately evaluated. METHODS We randomly assigned adults with primary HIV infection to ART for 48 weeks, ART for 12 weeks, or no ART (standard of care), with treatment initiated within 6 months after seroconversion. The primary end point ...
متن کاملReduced antiretroviral drug susceptibility among patients with primary HIV infection.
CONTEXT The transmission of drug-resistant human immunodeficiency virus (HIV) has been documented, but the prevalence of such transmission is unknown. OBJECTIVE To assess the spectrum and frequency of antiretroviral susceptibility among subjects with primary HIV infection. DESIGN, SETTING, AND PATIENTS Retrospective analysis of 141 subjects identified from clinical research centers in 5 maj...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2007
ISSN: 0022-1899,1537-6613
DOI: 10.1086/512090